Changesintheitinerarycouldbecausedbyunforeseendifficultieslocalpoliticalconditions,mechanicalbreakdown,weather,sicknessorotherunforeseeablecircumstances.
What's a sentence that uses these characters?
Changes in the itinerary could be caused by unforeseen difficulties local political conditions, mechanical breakdown, weather, sickness or other unforeseeable circumstances.