Ina90daysoralstudyonbeagledogs,whichdailyfor7days/weekwereadministeredthesubstanceingelatinecapsulesatthedoses0,35,75and150mg/kgbw/day,noessentialsubstancerelatedeffectsatanyoftheusedconcentrationswereobserved.

Please segment the words:
In a 90 days oral study on beagle dogs, which daily for 7 days/week were administered the substance in gelatine capsules at the doses 0, 35, 75 and 150 mg/kg bw/day, no essential substance related effects at any of the used concentrations were observed.