Please add spaces between words: Thereareavarietyofapplicationsforthisnewmethodology,withmitochondrialdysfunctionisimplicatedinmanyhumandiseases,suchasDiabetesmellitus7,obesity8,multiplesclerosis9,Parkinson'sdiseases10,Alzheimer'sdisease11andsometypeofcancers12.Importantly,ourworkisperformedinvivo,whereallenvironmentalinfluences-suchascytokines,development-relatedgrowthetc-areactive,therebyprovidingaphysiologicallyrelevantviewinvivorespirationandmetabolicprofile.
There are a variety of applications for this new methodology, with mitochondrial dysfunction is implicated in many human diseases, such as Diabetes mellitus7, obesity8, multiple sclerosis9, Parkinson's diseases10, Alzheimer's disease11 and some type of cancers12. Importantly, our work is performed in vivo, where all environmental influences - such as cytokines, development-related growth etc - are active, thereby providing a physiologically relevant view in vivo respiration and metabolic profile.